肉桂醛对肺癌细胞A549具有体外抑制作用

Cinnamaldehyde to lung cancer cell line A549 has obvious antitumor activity in vitro

目的探讨肉桂醛对肺癌细胞株A549的生长抑制作用。方法采用噻唑蓝比色法检测肉桂醛对体外培养的人肺癌细胞系A-549 细胞株的生长抑制作用,计算半数抑制浓度。结果肉桂醛能抑制人肺癌细胞系A-549 细胞增殖,且呈剂量依赖性,IC50值为0.36 mg/ml。结论在体外,肉桂醛对肺癌细胞株A549具有明显抗肿瘤活性。

Objective To explore the inhibition of cinnamaldehyde to the growth of lung cancer cell fines A549. Methods Using thiazole blue colorimetry to detect the inhibition of cinnamaldehyde on the growth of human lung cancer cell line A - 549 cell lines in vitro, calculate the half inhibitory concentration. Results Cinnamaldehyde inhibits the proliferation of human lung cancer cell line A - 549 cells, which is dose dependent, IC50 alue concentration is 0.36 mg/ml. Conclusion In vitro, cinnamaldehyde has an obvious antitumor activity to lung cancer cell line A549.