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多囊卵巢综合征采用二甲双胍治疗对促排卵作用探讨 被引量:5

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摘要 目的:观察采用二甲双胍在治疗多囊卵巢综合征(PCOS)中对促排卵的作用。方法:选择笔者所在医院2013年1-7月收治的109例PCOS患者,按照随机数字表法将患者分为治疗组55例和对照组54例。给予治疗组患者服用二甲双胍,给予对照组患者维生素C作为安慰剂,分别于给药的第2周、第4周及第5周测量患者血孕酮(P)值,5周后仍无排卵者,全部给予克罗米芬,再次观察两组患者第7、8周排卵情况。结果:第4周、第5周两组患者孕酮≥3μg/L例数比较差异有统计学意义(P<0.05)。第7周、第8周两组患者孕酮≥3μg/L例数比较差异有统计学意义(P<0.05)。治疗第5周时,治疗组患者治疗前后主要生化指标均有不同程度改善,与治疗前比较差异均有统计学意义(P<0.05)。结论:采用二甲双胍治疗PCOS是一种长期的治疗手段,可减轻患者胰岛素抵抗的同时,具有明显的促排卵作用,对治疗PCOS具有重要的意义。
出处 《中外医学研究》 2014年第18期40-41,共2页 CHINESE AND FOREIGN MEDICAL RESEARCH
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