不典型疟疾五例诊治分析

Atypical Malaria:Analysis of Five Cases

目的探讨不典型疟疾的临床诊治特点。方法对2001年4月—2013年5月安徽财经大学医院诊治的5例不典型疟疾患者的临床资料、实验室检查及诊断资料进行回顾性分析。结果 5例不典型疟疾患者的临床症状不典型,热型不规律;于春季和春夏之交发病,流行病学特点不明显;血涂片找疟原虫阴性;使用复方奎宁行诊断性治疗效果良好后确诊。结论临床对于排除其他恶性疾病引起的高热患者应考虑不典型疟疾的可能,疟原虫检查阴性不能排除本病的可能;本病需与上呼吸道感染、败血症等疾病鉴别,常规退热或抗感染治疗无效后可采用复方奎宁进行诊断性治疗。

Objective To explore the clinical features of atypical malaria.Methods Five patients with atypical malaria in Hospital of Anhui Finance and Economics University from Apirl 2001 to May 2013 were selected,the clinical data,laboratory results and diagnosis information were analyzed retrospectively.Results The clinical symptoms of 5 patients were atypical,fever type irregular,starting in spring or at the end of spring and the beginning of summer,with unobvious epidemiological features.By blood tests,the plasmodium was negative.Compound quinine was used to perform diagnostic treatment and then diagnosed.Conclusion The possibility of atypical malaria should be considered after excluding the other malignant diseases in hyperpyrexia patients.Tested negative for the parasite can not exclude the possibility of this disease,this disease should be distinguished from upper respiratory infection,septicemia and other diseases.Compound quinine can be used to do diagnostic treatment after ineffective treatments of conventional antipyretic or anti-infection.