短柱八角的化学成分研究

Chemical constituents of Illicium brevistylum

目的研究八角科植物短柱八角Illicium brevistylum干皮的化学成分。方法运用硅胶色谱、凝胶（Sephadex LH-20）色谱和ODS反相色谱等方法进行分离和纯化,根据理化性质以及核磁共振、质谱等波谱技术进行结构鉴定。结果从短柱八角干皮醋酸乙酯部位分离得到了12个化合物,分别鉴定为槲皮素-3-O-β-吡喃木糖苷（1）、槲皮素（2）、二氢山柰酚（3）、山柰酚（4）、五灵脂酸V（5）、儿茶素（6）、3,5,7-三羟基色酮-3-O-α-L-阿拉伯吡喃糖苷（7）、大八角素（8）、莽草内酯B（9）、7-O-乙酰基-莽草内酯B（10）、红花八角素C（11）、花旗松素-3-O-β-D-吡喃木糖苷（12）。结论化合物5、7为首次从八角科植物中分离得到,化合物1、6、8-11均为首次从该植物中分离得到。

Objective To isolate and identify the chemical constituents in the ethanol extract from the barks of Illicium brevistylum.Methods The barks of I.brevistylum were extracted by 80% ethanol then partitioned by system solvents with different polarity.The ethyl acetate extract was separated on silica gel,Sephadex LH-20,and ODS columns.The isolated compounds were identified by physicochemical properties and spectral analyses.Results Twelve compounds were isolated and purified from the ethyl acetate extract of I.brevistylum and the structures were identified as quercetin 3-O-β-xylopyranoside（1）,quercetin（2）,dihydro kaempferol（3）,kaempferol（4）,wulingzhic acid V（5）,catechin（6）,3,5,7-trihydroxylchromone-3-O-α-L-arabinopyranoside（7）,majucin（8）,anislactone B（9）,7-O-acetylanislactone B（10）,dunnianolide C（11）,and taxifolin-3-O-β-xylopyranoside（12）.Conclusion Compounds 5 and 7 are obtained from the plants in Illiciaceae for the first time and compounds 1,6,and 8—11 are firstly isolated from I.brevistylum.