头孢布烯与氧氟沙星治疗泌尿系感染的比较

Ceftibuten vs ofloxacin in treating urinary tract infection

目的 :比较头孢布烯与氧氟沙星治疗泌尿系感染的疗效。方法 :10 2例病人 (男性 4 5例 ,女性57例 ,年龄 4 9a±s 13a)随机分为 2组 (各 51例 ) ,头孢布烯组 (复发性泌尿系感染 31例 ,原发性泌尿系感染 2 0例 )用头孢布烯 4 0 0mg ,po ,qd ,疗程10 .4d± 2 .7d ;氧氟沙星组 (复发性泌尿系感染 30例 ,原发性泌尿系感染 2 1例 )用氧氟沙星 10 0mg ,po ,tid ,疗程 10d± 3d。结果 :2组总有效率分别为92 %和 76% (P <0 .0 5) ;致病菌总清除率分别为92 %和 78% (P >0 .0 5)。结论

AIM: To compare the effects of ceftibuten and ofloxacin in treating urinary tract infections (UTI). METHODS: The 102 UTI patients (M 45, F 57; age 49 a± s 13 a) were divided randomly into two groups (each group including 51 patients). The ceftibuten group (31 secondry UTI patients and 20 primary UTI patients) were given ceftibuten 400 mg, po , qd for 10.4 d±2.7 d. The ofloxacin group (30 secondary UTI patients and 21 primary UTI patients) were given ofloxacin 100 mg, po , tid for 10 d±3 d. RESULTS: The total effect rate of two groups was 92 % and 76 %( P < 0.05 ) respectively. The total bacterial clearance rate of two group was 92 % and 78 % ( P >0.05) respectively. CONCLUSION: Ceftibuten is more effective than ofloxacin in treating UTI patients.