复方克林霉素搽剂治疗寻常痤疮

Compound clindamycin liniment in treatment of acne vulgaris

目的 :观察复方克林霉素搽剂治疗寻常痤疮的疗效。方法 :采用开放、多中心临床试验方法以复方克林霉素搽剂治疗 153例寻常痤疮病人 (男性53例 ,女性 10 0例 ,年龄 2 2a±s 6a) ,每日 3次涂于面部 ,连续 4wk ,每 2wk随访。结果 :复方克林霉素搽剂治疗寻常痤疮 ,4wk总显效率达 83.0 % ,对脓疱和丘疹的总有效率分别为 96.1%和 80 .7% ,不良反应率为 1.9%。结论 :复方克林霉素搽剂治疗痤疮疗效显著 ,安全性高 。

AIM: To observe the effect of compound clindamycin liniment on acne vulgaris. METHODS: A multi centre, open label trial of compound clindamycin liniment in treating acne vulgaris. One hundred and fifty three patients used compound clindamycin liniment on face three times per day for 4 wk. RESULTS: The total excellent response rate was 83.0%. The total effect rate on pustule and papule was 96.1% and 80.7% respectively. The adverse reaction rate was 1.9%. CONCLUSION: Compound clindamycin liniment is an effective and safe drug in the treatment of acne vulgaris.