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牙龈素在牙龈卟啉单胞菌生长及牙周致病过程中的作用 被引量:5

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摘要 牙龈素是慢性牙周炎的重要致病菌——牙龈卟啉单胞菌的最重要毒力因子。作为一组半胱氨酸蛋白酶,牙龈素能结合并降解多种宿主蛋白质。本文总结了目前对牙龈素的结构和功能的研究,主要从牙龈素对牙龈卟啉单胞菌生长代谢、对牙周组织的致病作用及宿主免疫的影响三个方面阐述。
作者 张瑞 孙卫斌
出处 《口腔生物医学》 2014年第2期100-102,共3页 Oral Biomedicine
基金 国家自然科学基金(81271155)
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参考文献29

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共引文献1

同被引文献73

  • 1曾宪涛,高岭,刘得玺,郭毅,罗志晓,冷卫东.牙周病与口腔癌相关性的Meta分析[J].湖北医药学院学报,2012,31(5):390-394. 被引量:14
  • 2张绮霞,杨秋波,杨圣辉.牙龈卟啉单胞菌血红素结合蛋白的研究[J].北京口腔医学,2006,14(2):149-151. 被引量:2
  • 3林梅,杨秋波,杨圣辉.牙龈卟啉单胞菌对铁和亚铁血红素的摄取机制[J].北京口腔医学,2007,15(2):118-120. 被引量:1
  • 4方厂云,苏征,陈蕾,樊明文,翦新春,陈智.牙龈卟啉单胞菌脂多糖对人牙周膜成纤维细胞胶原吞噬作用的影响[J].华西口腔医学杂志,2007,25(4):339-341. 被引量:11
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