血糖干预对妊娠期糖尿病患者妊娠结局的影响

Blood sugar intervention influencing on pregnancy outcome of gestational diabetes mellitus

目的探讨血糖干预对妊娠期糖尿病(GDM)患者母婴妊娠结局的影响。方法根据血糖控制情况将GDM患者分为血糖控制良好组(83例)和控制不良组(57例),比较两组母婴妊娠结局、并发症发生率等。结果控制不良组的妊高症、羊水过多、酮症酸中毒和产后出血等孕产妇并发症发生率明显高于控制良好组(χ2值分别为4.690、5.682、4.688和5.682,P<0.05);而控制不良组的早产儿、巨大儿、新生儿低血糖、新生儿窒息和高胆红素血症等围产儿并发症发生率均明显高于控制良好组(χ2值分别为5.882、5.682、5.882、6.992和9.399,P均<0.05)。结论应高度重视GDM对妊娠的危害,做到早诊断、早治疗,控制妊娠期血糖水平,可有效降低GDM对妊娠结局的影响。

Objective To explore the effect of blood sugar intervention affecting pregnancy outcome. Methods GDM cases were divided into good blood sugar control group （83 cases） and not good control group （57 cases） according to blood sugar control condition. Pregnancy outcome and complications were compared between the two groups. Results The complications incidence rates of pregnancy-induced hypertension syndrome, hydramnios, ketoacidosis, postpartum hemorrhage, uterine-incision delivery, premature delivery, large for date infant, neonatal asphyxia, hypoglycemia of newborn and hyperbilirubinemia in not good control group were much higher than not good control group （P〈0.05）.Conclusion We should think highly of the harm of GDM, early discovering and treating GDM, especially controlling blood sugar level. It could cut down the effect of GDM to pregnancy outcome.