防风质量标准的研究

Studies on Quality Specification Standards for Saposhnicovia divaricata (Turcz.) Schischk

目的 :对防风药材及市售饮片进行质控标准研究。方法 :TLC法检定防风药材及饮片中 4个色原酮类成分 ,HPLC法测定防风中 2个主要有效成分的含量。结果和结论 :防风药材和饮片中必须同时检定出升麻素 ,亥茅酚苷 ,5 O 甲基维斯阿米醇苷及升麻苷 ;防风药材和饮片中有效成分升麻苷及 5 O 甲基维斯阿米醇苷的含量均不得低于 0 .12 %。

Objective:To work out a qualitative-quantitative standard for Saposhnikovia divaricata.Method:TLC and HPLC were adopted.Result:Four chromone compounds were identified by TLC,and the contents of two chromone compounds were determined by HPLC.Conclusion:Prim-O-glucosylcimifugin,4′-O-β-D-glucosyl-5-O-methylvisamminol,sec-O-glucosylhamaudol and cimifugin should be present simultaneously in S. divaricata.The contents of prim-O-glucosylcimifugin and 4′-O-β-D-glucosyl-5-O-methylvisamminol in S. divaricata should not be lower than 0.12% respectively.