摘要
目的:探讨影响肝豆状核变性(WD)患者心理状况的相关因素。方法:记录82例住院WD患者的一般临床资料、头颅CT或MR结果,采用统一wilson病神经功能评分标准(UWDRS)、Nazer肝功能评分标准、艾森克个性问卷(EPQ)、社会支持评定量表(SSRS)以及症状自评量表(Scl-90)对其进行评估及测查。统计分析可能影响其心理状况的各项因素。结果:WD患者不良心理问题发生率为46.3%。与其心理状况相关的因素有性格神经质维度、神经功能损害程度、肝功能损害程度、社会支持度及颅脑影像病变范围。多因素Logistic回归分析示神经功能损害(OR=8.708)、头颅影像病变范围(OR=4.889)是影响WD患者心理状况的独立相关因素。结论:减轻神经功能损害并恢复神经功能可能是改善WD患者心理状况根本的途径。
Objective:To study the related factors affecting mental health of patients with wilson disease ( WD) .Methods:We used Eysenck Personality Questionnaire ( EPQ ) , Unified Wilson's Disease Rating Scale ( UWDRS ) , Nazer Scale , Social Support Rating Scale(SSRS) and Symptom Checklist 90 (Scl-90) to investigate 82 patients with WD and recorded their basic clinical data as well as head imaging changes .The factors which may affact its mental health were analyzed .Results:The prevalence rates of psychological dis-order of the patients with WD was 46.3%.Their mental health was related to the neuroticism , degree of neurologic lesion , degree of liver lesion, social support and imaging range of intracranial lesions .Neurologic lesion(OR=8.708) and imaging range of intracranial lesions (OR=4.889) were independent Ly related factors in multiariable Logistic regression analysis .Conclusion:To reduce the neu-rologic lesion and restore the function of neurologic can improve the mental health of patient with WD .
出处
《牡丹江医学院学报》
2014年第3期19-22,共4页
Journal of Mudanjiang Medical University
基金
广东省卫生厅基金项目(2010310)