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阿托伐他汀钙对冠心病患者颈动脉粥样硬化斑块的影响 被引量:3

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摘要 目的:研究阿托伐他汀钙对冠心病合并颈动脉粥样硬化斑块患者的临床疗效。方法:选取我院收治的冠心病合并颈动脉粥样硬化斑块患者82例,随机均分为实验组与对照组,对照组维持原冠心病常规治疗,实验组在对照组的基础上服用阿托伐他汀钙20 mg/d,持续1年,观察对比两组患者治疗后的临床疗效。结果:两组治疗1年后,实验组患者在TC、TG、LDL-C、HCY等指标上显著低于对照组,而HDL-C水平显著高于对照组(P<0.05);实验组患者的IMT平均为(1.02士0.13)mm,斑块积分平均为(3.35士0.32),对照组患者的IMT平均为(1.33士0.24)mm,斑块积分平均为(3.84士0.38),两组在IMT、斑块积分上存在显著性差异(P<0.05)。结论:阿托伐他汀钙治疗颈动脉粥样硬化斑块疗效显著,但一定要在治疗过程中加强预防患者血清中HDL-C的升高。
作者 李修敏
出处 《牡丹江医学院学报》 2014年第3期48-49,共2页 Journal of Mudanjiang Medical University
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