摘要
免疫球蛋白超家族补体受体(complement receptor of the immunoglobulin superfamily,CRIg)可通过T细胞和细胞因子等调节免疫反应,参与多种疾病发生。文中对动物模型研究CRIg在免疫性肝损伤、肠缺血再灌注损伤、Ⅰ型糖尿病、自身免疫性葡萄膜炎及类风湿关节炎等疾病发生机制中的作用作一综述。
Complement receptor of the immunoglobulin superfamily( CRIg) can regulate immune reactions via T cells and cytokines and is involved in various diseases.The effect of CRIg on the pathogenesis of immunological liver injury,intestinal ischemiareperfusion injury,type Ⅰ diabetes mellitus,experimental autoimmune uveoretinitis,and rheumatoid arthritis etc.in animal models of disease are reviewed in this article.
出处
《医学研究生学报》
CAS
北大核心
2014年第6期648-650,共3页
Journal of Medical Postgraduates
基金
国家自然科学基金(30360037)
关键词
免疫球蛋白超家族补体受体
疾病
动物模型
Complement receptor of the immunoglobulin superfamily
Disease
Animal models