小涎腺局灶性增生的临床病理观察

A study on clinicopthology the focal hyperplasia of minor salivary gland

目的 涎腺局灶性增生为发生于口腔小涎腺的少见病 ,临床常误诊为良性肿瘤或其他病变 ,为提高临床病理诊断水平 ,本文进行了总结。方法 复习 6 2 8例小涎腺肿瘤及瘤样病变的病理切片中 ,有 9例属于本病。结果 9例的发生部位以腭部最多见 (4 /9) ,其次为上唇 (2 /9)、颊、磨牙后垫及舌各 1例。临床表现增生物较小 ,为柔软的实性团块 ,与周围组织之间无明显界限。病理表现为大量粘液腺泡的聚集 ,腺导管基本正常 ,无炎症或散在少量慢性炎症细胞 ,偶见少量腺泡的细胞膜消失 ,腺泡融合 ,增生物与周围腺体之间无明显界限。结论 本病临床表现为缓慢增生的肿块 ,作出准确诊断较困难 ,只有手术后病理检查才能确诊。

Objective The purpose of the present study was to give more recognition clinically and pathologically.Methods The files were from the oral pathology of stomatology of Bejing medical university,628 cases of minor salivary gland tumor and tumor-like were retrieved.The lesion of 9 cases were diagnosed as focal hyperplasia.Results The most common sit was the palate (4/9).Few lesions were found in the upper labial mucosa (2/9).1 case was found in the buccal mucosa and mandibular retromolar pad and the tongue respectively.7 cases occured in males and 2 in females.The age distribution of the patients ranged from 29 to 68 years.All the lesions appeared as localized masses and most of them were discribed by the clinicians as firm or soft swellings.Histomorphologic pattern showed a numerous hyperplasia mucous acinic.Conclusion The focal hyperplasia of minor salivary glands appears as a tumor.It is very difficult to make correct diagnosis but it is easily distingushed histologically from salivary neoplasms.