氟化牛奶再矿化及抗龋作用的体内观察

An in vivo study on remineralization and anti-caries effect of fluoridated milk

目的 探索氟化牛奶在口腔局部的防龋作用机制。方法 利用口内装置 ,采用交叉对照的试验方法 ,观察氟化牛奶在口腔局部的再矿化作用和抗龋作用。结果 氟化牛奶有明显的再矿化作用 ,本试验条件下未观察到抗龋作用。结论 氟化牛奶在口腔局部的作用机制主要是再矿化。

Objective To explore the local mechanism of caries prevention of fluoridated milk.Methods Decalcified bovine enamel blocks were set onto each removable appliance worn by 8 subjects divided into two groups.Each group subjects drank F-milk and F-water twice a day respectively for 28 days in a cross-over fashion.Results Both two groups had their active effects in remineralization and even better effect remineralization in F-milk than F-water,but anti-caries effect was not observed in both groups.Conclusion The local mechanism of fluoridated milk is to facilitate the remineralization of enamel mainly.