摘要
Cell signaling has been well recognized as a highly complex process, which mainly delivers environmental information into ceils. A number of regutating mechanisms of cell signaling have been uncovered in great details. Recently,IMCB also published several articles on new members or regulating mechanisms of various cell signaling pathways (Wu, 2013). In this issue, the collection of four articles will add new aspects to understanding the molecular mechanisms of cell signaling.