异性固定性伴间HIV传播影响因素的logistic回归分析

Influencing Factors of HIV Transmission Between Fixed Heterosexual Sexual Partners

目的分析艾滋病感染者(患者)其配偶(固定性伴)受感染的影响因素,为防止艾滋病的二代传播提供参考建议。方法采用现况研究了解四川省3地区的艾滋病感染者(患者)及其配偶(固定性伴)HIV的感染现状,使用非条件logistic回归模型分析HIV异性性传播的影响因素。结果单因素logistic回归分析显示,艾滋病感染者(患者)其配偶(固定性伴)受感染的影响因素有:艾滋病感染者(患者)接受艾滋病药物治疗情况(OR=0.498,P=0.027)、性行为频率(OR=4.065,P=0.047)、配偶(固定性伴)的吸毒情况(OR=2.195,P=0.021)、配偶(固定性伴)认为自身感染HIV的可能性(OR=0.089,P=0.000);多因素logistic回归分析显示,配偶认为自己感染HIV的风险(OR=0.077,P=0.000)和每周1次及以上的性行为频率(OR=5.148,P=0.045)是影响艾滋病感染者(患者)其配偶(固定性伴)受感染的主要影响因素。结论调查地区艾滋病感染者(患者)及其配偶(固定性伴)间的性行为频率以及配偶认为自己感染HIV的可能性是影响HIV在异性固定性伴间传播的主要因素。因此,加强异性固定性伴间的性行为干预是防止艾滋病二代传播的重要途径。

Objective To analyze the influencing factors of HIV transmission between fixed heterosexual sexual partners, and thus to provide a reference for preventing the spread of AIDS. Methods Filed study was carried out to understand HIV infection status quo of HIV patients and their spouses （ regular sexual partners） in the three areas of Sichuan province ; influencing factors of heterosexual transmission of HIV were indentified with the non -conditional logistic regression model. Results Univariate regression showed that the influencing factors included ： AIDS infected persons （patients） receivinz HIV medication situation （ OR = 0.498 ,p =0. 027）, the frequency of sexual activity among them （OR = 4. 065, P = 0. 047） , the drug abuse s{tuation of the spouse （regular sexual partners） （OR =2. 195, P = 0. 021 ） , spouse＇ （ regular sexual partner） own awareness of HIV infection risk （ OR = 0. 089, P = 0. 000）. The multivariate logistic regression analysis showed the influencing factors： spouse＇ （regular sexual partner） own awareness of HIV infection risk （OR =0. 077, P = 0. 000）, and sex frequency that more than once a week （ OR = 5. 148, P = 0. 045 ）. Conclusion The main influencing factors of HIV transmission between fixed heterosexual sexual partners are frequency of sex and spouse＇ （ regular sexual partner） own awareness of HIV infection risk. Therefore, strengthening the sexual behavior interventions among fixed heterosexual sexual partners is an important way to prevent the secondary transmission of AIDS.