2006-2008年汕头市病毒性脑炎病原监测

Pathogenic Surveillance of Viral Encephalitis in Shantou City,2006-2008

目的通过对汕头市病毒性脑炎的病原监测,了解该地区病毒性脑炎的病原谱及发病情况。方法哨点医院对2006-2008年就诊的疑似脑炎病例进行血液及脑脊液标本采集,运送至汕头市疾病预防控制中心,采用ELISA法对脑炎疑似标本进行乙脑病毒(JEV)IgM、单纯疱疹病毒(HSV)IgM、巨细胞病毒(CMV)IgM、科萨奇病毒(COXV)IgM、埃可病毒(ECHO)IgM、腺病毒(ADV)IgM 6种病毒抗体项目检测。结果监测期间共接收148例疑似脑炎病例,采集的标本总共检出病毒抗体阳性标本19份,病毒总阳性率为12.8%。其中JEV阳性2份;HSV阳性6份;CMV抗体阳性1份;ECHO抗体阳性1份;ADV抗体阳性7份;HSV和ADV抗体阳性1份;ECHO和ADV抗体阳性1份。结论汕头市病毒性脑炎病原以ADV和HSV阳性率较高,需加强此类病毒的防控。

Objective To understand pathogen spectrum and morbidity of viral encephalitis in Shantou city. Methods Suspected cases of encephalitis during 2006 - 2008 were collected and sampled in terms of blood and CSF. Enzyme - linked immunosorbent assay （ELISA） was adopted to detect viral encephalitis from the speci- mens. Results Nineteen positive virus antibody were detected in 19 samples, with a positive rate of 12.8%. The 19 positive samples were composed by 2 JEV IgM, 6 HSV IgM, one CMV IgM, one Eehovirus IgM, and 7 ADV IgM. While the other 2 samples were detected as two sorts of virus IgM, specifically HSV ＋ ADV and ECHO ＋ ADV. Conclusion The viral encephalitis pathogen is predominated by ADV and HSV, and thus perti- nent preventive measures against the two virus should be strengthened.