慢性病毒性肝炎重症化倾向期中西医结合诊疗方案临床疗效研究

Clinical Study of Integrated Chinese and Western Medicine Treatment of Chronic Severe Viral Hepatitis Tendency Period

目的:明确慢性病毒性肝炎重症化倾向期中西医结合诊疗方案的临床治疗效果,为进一步优化中西医结合诊疗方案提供临床支持。方法:采用随机、临床对照研究,将56例慢性病毒性肝炎重症化倾向期患者随机分为对照组(28例)和治疗组(28例),对照组予西医综合治疗,治疗组在西医综合治疗的基础上结合中医辨证治疗。在治疗前后观察2组患者的症状积分、肝功能指标、肝衰竭转化及不良反应情况。结果:慢性病毒性肝炎重症化倾向期患者在西医综合治疗的基础上结合中医辨证治疗,能显著改善患者症状积分,促进肝功能的恢复,减少病情向肝衰竭中、重度发展,临床总有效率优于对照组。结论:慢性病毒性肝炎重症化倾向期中西医结合诊疗方案能更全面地发挥中医药治疗重症化倾向期患者的治疗作用,且具有费用低、安全性高等优势,值得临床推广。

Ohjective：To determine the tendency of severe chronic viral midterm clinical outcomes, providing clinical support for the further optimization of integrative medicine program. Methods： A randomized, controlled clinical study was carried out. 56 patients with severe chronic tendency of viral hepatitis were randomly divided into control group （ 28 eases ）and treatment group （ 28 cases ）and control group used Western medicine and treatment group combined therapy. We observed symptom scores before and after treatment, liver function, liver failure and adverse reactions transtormation in two groups. Results ： TCM and Western medicine treatment for viral severe tendency of patients with chronic viral midterm t：an significantly improve patients＇ symptom scores, and promote the recovery of liver function, reduce disease to liver failure, severe development and clinical total optimization efficieney. Conclusion ： Severe chronic viral tendeney midterm ：integrative treatment program can play a fuller treatment of severe tendency and has low cost, high security and other advantages, and is worthy of promotion.