2010年广西成年人血脂异常患病率及其危险因素研究

Prevalence rate and risk factors of dyslipidemia among adults in Guangxi Province

目的了解广西18岁及以上人群血脂异常患病率及其危险因素,为制定相应干预策略提供科学依据。方法 2010年在广西6个监测县(区),采用多阶段分层随机整群抽样方法,调查了3600名18岁及以上居民,对其进行问卷调查、体格检查及血脂、血糖测定。对样本进行复杂加权后,计算血脂异常患病率并分析其影响因素。结果2010年广西成年人血脂异常患病率为53.0%,男、女血脂异常患病率分别为58.0%和47.6%,城市和农村居民血脂异常患病率分别为56.7%和52.0%。高胆固醇血症、高甘油三酯血症、低高密度脂蛋白胆固醇血症和高低密度脂蛋白胆固醇血症患病率分别为5.0%、10.1%、46.2%和3.8%。血脂异常类型以高甘油三酯血症、低高密度脂蛋白胆固醇血症为主。多因素非条件logistic回归分析结果显示,男性(OR=1.533)、超重(OR=1.301)、肥胖(OR=1.480)、中心性肥胖(OR=2.104)和蔬菜摄入不足(OR=1.293)是影响广西成年人血脂异常的危险因素,身体活动活跃(OR=0.336)和身体活动充分(OR=O.575)是血脂异常的保护因素。结论 2010年广西成年人血脂异常患病率较高,血脂异常类型以高甘油三脂血症、低高密度脂蛋白胆固醇血症为主,应加强血脂异常的综合防治力度。

Objective To explore the prevalence rate and related risk factors of dyslipidemia among adults in Guangxi Province, and to provide evidence for prevention and intervention. Methods Inhabitants aged 18 years and over were selected by multi-stage stratified cluster random sampling from 6 surveillance points in Guangxi Province in 2010. Questionnaire survey, physical examination and biochemical detection were conducted among the residents. After the complex weighting, the prevalence rate and risk factors of dyslipidemia were analyzed. Results The total prevalence rate of dyslipidemia was 53.0%in the adults in Guangxi. and the prevalence rates in males and females were 58.0%and 47.6%respectively. The prevalence rates of dyslipidemia in urban and rural residents was 56.7%and 52.0%respectively. The prevalence rates of hypercholesterolemia, hypertriglyceridemia, low HDL-C and high LDL-C were 5.0%, 10.1%, 46.2%and 3.8%, respectively. Multivariate logistic regression analysis showed that male （OR=1.533）, overweight （OR=1.301）, obesity（OR=1.480）, central obesity（OR=2.104） and shortage of vegetables intake（OR=1.293） were the risk factors, and the vigorous physical activity （OR=0.336）and moderate physical activity （OR=0.575） were the protective factors for dyslipidemia in the adults of Guangxi. Conclusions The prevalence rate of dyslipidemia in Guangxi is relative high and the hypertriglyceridemia and low HDL-C are the most predominant. Comprehensive measure should be taken to prevent the people from getting dyslipidemia.