6HARRIS G. Prilosec's maker switches users to nexium[ J]. Thwar- ting Generics, WALL ST. J. ,2002,13 ( 6 ) :23 - 24.
7Pub. L. No. 97-414. The Orphan Drug Act[ S]. Amended the Fed- eral Food, Drug and Cosmetic Act ( FFDCA ) as of January, 4, 1983.
8EUREK SE. Hath-Waxman reform and accelerated market entry of generic drug: is faster necessarily better[ J]. Duke L Tech Rev, 2003,22(16) :18 - 19.
959th WMA General Assembly, Seoul, October 2008: the Declaration of Helsinki. [EB/OL]. [2010 -11-18 ]http://www.wma.net/en/30publications/ 10policies/b3/index.html.
10NIH.Overview of the NIH Roadmap. http://nihroadmap.nih.gov/overview.asp . 2008