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高血压治疗效果与动脉僵硬指数的相关性

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摘要 目的研究高血压患者经治疗后,血压控制效果与动脉僵硬指数(AASI)的关系。方法以97例高血压患者为研究对象,其中男性72例,女性25例,平均年龄(60.0±16.4)岁。按照血压是否控制正常将患者分成控制组(28例)和未控制组(69例)。患者均经过6个月以上的抗高血压治疗,记录其24h动态血压,计算AASI、脉压(PP)和脉压指数(PPI),并做相关性分析。结果控制组患者AASI、PPI(分别为0.41±0.20、0.72±0.03)与未控制组(分别为0.43±0.18、0.72±0.04)比较,差异均无统计学意义(t值分别为-0.585、-0.239,P>0.05);控制组患者PP[(48.36±8.44)mmHg]与未控制组[(61.33±12.47)mmHg]比较,差异有统计学意义(t=-5.047,P<0.01);AASI与PP呈正相关(r=0.232,P=0.022),PP与PPI呈负相关(r=-0.807,P<0.01),AASI与PPI无相关性(r=0.131,P>0.05)。结论 AASI、PP和PPI均可反映患者动脉僵硬程度,但在抗高血压治疗中,短期未见到AASI的明显改善。
作者 李丽华
出处 《中国慢性病预防与控制》 CAS 2014年第3期339-340,共2页 Chinese Journal of Prevention and Control of Chronic Diseases
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