新生儿溶血88例的临床治疗分析

Clinical Treatment of 88 Cases With Hemolytic Disease of the Newborn

目的分析新生儿溶血病88例的临床治疗。方法资料选自2011-04/2013-04在东莞三局医院就诊的新生儿溶血病患儿88例,对治疗有效率、并发症的发生情况进行分析。结果在检测以及综合治疗之后治疗的总有效率为100%;术中以及术后并发症的发生率为0%;31例患儿的治疗方法为换血疗法,换血率为35.23%,且换血后胆红素明显降低,再结合药物和蓝光治疗后7～14 d患儿康复。结论在新生儿溶血病的临床治疗中及早发现病情且予以相应治疗可避免高胆红素脑病等各类疾病发生,亦可将该病治疗的总有效率显著提高。

Objective To analyze the clinical treatment of 88 cases of hemolytic disease of the newborn（ HDN）. Methods Data of 88 HDN cases visiting The Third Engineering Bureau Hospital of Dongguan during Apr.,2011 to Apr.,2013 were collected,and the treatment efficiency and complication occurrence were analyzed. Results The total effective rate was 100% after examination and comprehensive treatments. The complication rate in and after operation were both 0%. There were 31 cases were conducted exchange transfusion therapy,with an exchange rate of 35. 23%. The bilirubin level decreased significantly after exchange and the patients recovered with drug therapy and blue light treatment for 7-14 d. Conclusion Timely examination and targeted treatments could prevent occurrence of diseases（ such as bilirubin encephalopathy） and also could significantly increase the total effective rate.