青岛地区某医院12年甲状腺癌发病模式变迁

The Variant Trend of Thyroid Cancer in a Certain Hospital in Qingdao during 12 Years

目的:探讨青岛地区某医院12年甲状腺癌的发病趋势和病理类型分布。方法:回顾性分析2001-2012年于青岛大学附属医院行手术切除的甲状腺癌患者的发病年龄、性别比例、手术数量以及病理类型构成比的变化。结果:12年来手术治疗甲状腺癌2421例,其中乳头状癌(PTC)占94.13%,滤泡状癌(FTC)占3.02%,髓样癌(MTC)占2.15%,未分化癌(ATC)占0.70%。甲状腺癌手术数量呈逐年递增趋势,尤以近4年升高显著,其病理类型以PTC为主,构成比例由79.63%上升至97.47%。四类甲状腺癌均以女性多见(男女比例1:1.38-1:4.37)。甲状腺癌的平均确诊年龄为46.80岁,PTC最低(46.48岁),ATC最高(64.25岁)。结论:青岛地区甲状腺癌发病数量呈逐年递增趋势,PTC是最常见的病理类型,其构成比例上升明显,其他类型相对下降。PTC的发病可能与高碘有关。

Objective： To explore the incidence trends and the pathological types of thyroid cancer in a certain hospital in Qingdao during 12 years. Methods： The patients who received thyroidectomy due to the thyroid cancer in the alTdiated hospital of Qingdao University between January 2001 and December 2012 were collected. A retrospective analysis was carried out to review the onset age, sex ratio, number of thyroid cancer surgery and pathological type composition ratio of patients. Results： The total number of thyroid cancer surgery were 2421 during 12 years, in which the papillary thyroid carcinoma （PTC） accounted for 94.13%, the follicular thyroid carcinoma （FTC） accounted for 3.02 %, the medullary thyroid carcinoma （MTC） accounted for 2.15 %, and the anaplastic thyroid carcinoma （ATC） accounted for 0.70 %. The number of thyroid cancer surgery showed an increasing trend year by year, especially in the past four years. Most of the pathological type was PTC, the composition ratio of which had increased fxom 79.63% to 97.47%. The incidence of woman was higher than that of man in four types of thyroid cancer （the ratio of male to female was 1：1.38-1：4.37）. The average diagnosed age of thyroid cancer was 46.80 years. PTC was the lowest （46.48 years）, and ATC was the highest （64,25 years）. Conclusion： The number of thyroid cancer showed a rising trend year by year in Qingdao. PTC was the most common pathological type of thyroid cancer, and it had an obvious increasing trend, while other types of thyroid cancer were relatively rare. The occurrence of PTC may be associated with high iodine intake.