后发性白内障防治进展

Prevention and treatment of posterior capsular opacification after cataract surgery

晶状体后囊膜混浊（posterior capsular opacification,PCO）也称后发性白内障,是白内障术后最常见的并发症.对其防治,以往研究多关注在白内障设备、操作技巧、IOL材料及设计方面,且已日臻完善.近些年更多关注PCO相关癌基因、凋亡基因等,但操作相对复杂,仅处于基础研究阶段;通过免疫手段干扰PCO发生,相对简单、廉价、可行,但效应短暂;药物治疗具有潜在的细胞毒性作用.

Posterior capsular opacification（PCO） remains the most common postoperative complication after cataract surgery.Previous studies had focused on improvements in surgical instruments and techniques,novel IOL biomaterials and IOL designs,and had been well developed.Lately more and more studies focused on cancer and apoptosis gene research which were much complex and only at a basic research stage.Using immunological techniques interfered PCO which were simply,cheap and feasible.And medical drugs for PCO which had potential cytotoxicity.