期刊文献+

右美托咪定在颅内动脉溶栓术中的应用效果 被引量:1

下载PDF
导出
摘要 急性脑梗死是一类严重危害人类健康的疾病,具有高发病率、高致残率、高病死率和治愈率低的特点,因此要迅速有效地实现血管再通,挽救半暗带,最终恢复神经缺损。溶栓时间窗是关键,溶栓越早,再通率越高,目前多主张以6h 内为宜[1]。但是由于患者就医时间延误,术中患者配合性差等诸多因素抵消了动脉溶栓术的获益。本研究旨在评估右美托咪定在颅内动脉溶栓术中有效性和安全性,为临床节约更多的时间。
出处 《湖北科技学院学报(医学版)》 2014年第3期217-219,共3页 Journal of Hubei University of Science and Technology(Medical Sciences)
  • 相关文献

参考文献5

二级参考文献28

  • 1胡建鹏,王键,郜峦,吕磊.局灶性脑缺血再灌注时神经元、胶质细胞形态变化与TNF-α、c-Myc表达相关的实验研究[J].中国病理生理杂志,2004,20(7):1251-1255. 被引量:8
  • 2孙晓江,许丹.急性脑梗死的溶栓治疗[J].世界临床药物,2005,26(3):152-155. 被引量:6
  • 3The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group.Tissue plasminogen activator for acute ischemic stroke.N Engl J Med,1995,333:1581-1587.
  • 4Furlan A,Higashida R,Wechsler L,et al.Intra-arterial prourokinase for acute ischemic stroke.The PROACT Ⅱ study:a randomized controlled trial.Prolyse in Acute Cerebral Thromboembolism.JAMA,1999,282:2003-2011.
  • 5Bamford J,Sandercock P,Dennis M,et al.Classification and natural history of clinically identifiable subtypes of cerebral infarction.Lancet,1991,337:1521-1526.
  • 6TIMI Study Group.The Thrombolysis in Myocardial Infarction (TIMI)trial.Phase Ⅰ findings.N Engl J Med 1985,312:932-936.
  • 7Bandera E Botteri M,Minelli C,et al.cerebral blood flow threshold of ischemic penumbra and infarct core in acute ischemic stroke:a systematic review.Stroke,2006,37:1334-1339.
  • 8Hacke W,Donnan G,Fieschi C,et al;ATLANRS Trials Investigators;ECASS Trials Investigators; NINDS rt-PA Study Group Investigators.Association of outcome with early stroke treatment:pooled analysis of ATLANTLS,ECASS,and NINDS rt-PA stroke trials.Lancet,2004,363:768-774.
  • 9Wahlgren N,Ahmed N,Dávalos A,et al;SITS investigators.Thrombolysis with alteplase 3-4-5 h after acute ischaemic stroke (SITS-ISTR):an observational study.Lancet,2008,372:1303-1309.
  • 10Bourekas EC,Slivka AP,Shah R,et al.Intraarterial thrombolytic therapy within 3 bours of the onset of stroke.Neurosurgery,2004,54:39-46.

共引文献30

同被引文献2

引证文献1

二级引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部