急性呼吸系感染疾病患者舌苔厚度与细胞凋亡的关系

Relationship Between the Thickness of the Tongue Coating and Cell Apoptosis in the Patients with Acute Infection of Respiratory Tract

从细胞凋亡角度研究舌苔的形成机理 ,探讨舌苔厚度和细胞凋亡的关系。采用电镜、荧光显微镜、流式细胞术等方法观察检测舌苔细胞中凋亡细胞的形态和数量。结果表明 :在舌苔细胞中存在具有典型凋亡形态特征的凋亡细胞。在急性呼吸系感染疾病患者中 ,中度舌苔凋亡指数显著大于轻度舌苔和重度舌苔 (P <0 0 5)。结论 :舌丝状乳头复层鳞状上皮细胞在终末分化过程中一部分细胞发生了细胞凋亡 ,舌苔厚度与细胞凋亡指数有一定关系。

The mechanism of the formation of the tongue coating and the relationship between the thickness of the tongue coating and cell apoptosis were studied by observing and examining the morphology and the amount of the apoptotic cells in the tongue coating with electron microscope, fluorescence microscope and flow cytometry apparatus. The results showed that in the tongue coating of patients with acute infection of respiratory tract, there were cells with typical apoptotic features, and the apoptotic index of the medium tongue coating was significantly greater than that of the light tongue coating or the heavy tongue coating ( P <0 05). It could be seen that during the process of terminal differentiation, some stratified squamous epithelial cells of filariform lingual papillae undergone apoptosis, and there was a certain relationship between the thickness of the tongue coating and the apoptotic index.