固本止咳胶囊治疗慢性支气管炎迁延期的临床研究

Clinical Study of the Effects of Gubenzhike Capsules on the Protracted Course of Chronic Bronchitis

对 45例慢性支气管炎迁延期肺肾两虚痰浊阻肺证患者随机分为治疗组和对照组 ,分别给予具有补肺益肾健脾化痰作用的固本止咳胶囊 (治疗组 ,30例 )和具有益气固表健脾补肾作用的固本咳喘片 (对照组 ,1 5例 )治疗。结果表明 :固本止咳胶囊对咳嗽、咯痰、喘息和哮喘音的有效率明显高于对照组 ;临床实验发现本药在改善患者肺功能、调节机体免疫等方面有较好效果。提示 :固本止咳胶囊对慢性支气管炎迁延期肺肾两虚痰浊阻肺证患者具有较好的疗效。

Cases of chronic bronchitis in the protracted course characterized by the TCM syndrome of deficiency of both the lung and kidney and obstruction of the lung by phlegm, were randomly divided into the treating group and the control group. The former (consisting of 30 cases) was given Gubenzhike Capsules (GCS) which possess the effects of tonifying the lung and benefiting the kidney, strengthening the spleen and dissolving phlegm; and the latter (consisting of 15 cases) was given Gubenkechuan Tablets (CTS) which possess the effects of nourishing qi, consolidating the exterior of the body, strengthening the spleen and tonifying the kidney. It was found that the effective rate of GCS in treating cough, expectoration, asthma, and wheeze was obviously higher than that of CTS, and the clinical tests showed that GCS could fairly improve pulmonary function, regulate immune function, etc. The results of study suggest that GCS have relatively good effects for treating patients with chronic bronchitis in the protracted course characterized by the TCM syndrome of deficiency of both the lung and kidney and obstruction of the lung by phlegm.