Prognostic value of coronary artery calcium score in patients with stable an-gina pectoris after percutaneous coronary intervention

ObjectivesTo 评估冠的动脉钙( CAC )的预示的值在经历了经皮的冠的干预(一种总线标准)的有稳定的心绞痛(树液)的病人的分数与经历了第一一种总线标准后面的多片计算机断层摄影术( MSCT )的树液一起的 334 个连续病人的 .MethodsA 总数从我们的机构被注册在之间2007年1月和2012年6月。CAC 分数根据标准 Agatston 钙得分算法被计算。复杂一种总线标准被定义为高压力汽球的使用，吻汽球或 rotablator。过程相关的复杂并发症包括了解剖，吸藏，穿孔，不 / 慢流动和紧急情况冠的动脉绕过 grafting。主要不利心脏的事件(向) 与 CAC 分数 &#x0003e 为心脏的 ischemic events.ResultsPatients 被定义为死亡，非致命的心肌的梗塞，目标损害 revascularization 和再进医院的一个联合结束点；300 (n = 145 ) 有的显著地更高的一种总线标准复杂性(13.1% 对 5.8% ， P = 0.017 ) 并且过程相关的复杂并发症的率(17.2% 对 7.4% ， P = 0.005 ) 与有 CAC 的病人获得 &#x02264 比；300 (n = 189 ) 。在 22.5 个月(4-72 月) 的中部的后续以后，有 CAC 的病人获得 &#x02264；300 比有 CAC 的那些病人获得 &#x0003e 的极大地不同；300 在累积大事宣传而结果并未举办的事幸存评价(88.9 对 79.0% ，木头等级 4.577， P = 0.032 ) 。在为另外的因素调整了以后，向的风险显著地更高[危险比率(HR ) ：4.3， 95% 信心间隔(95% CI ) ：2.4-8.2， P = 0.038 ] 在有一个 CAC 分数的病人 &#x0003e；300 与有一个更低的 CAC score.ConclusionsThe CAC 分数的病人相比是为在经历了一种总线标准的树液病人的向的一个独立预言者并且显示一种总线标准和过程相关的复杂并发症的复杂性。

Objectives To evaluate the prognostic value of the coronary artery calcium （CAC） score in patients with stable angina pectoris （SAP） who underwent percutaneous coronary intervention （PCI）. Methods A total of 334 consecutive patients with SAP who underwent first PCI following multi-slice computer tomography （MSCT） were enrolled from our institution between January 2007 and June 2012. The CAC score was calculated according to the standard Agatston calcium scoring algorithm. Complex PCI was defined as use of high pressure bal-loon, kissing balloon and/or rotablator. Procedure-related complications included dissection, occlusion, perforation, no/slow flow and emer-gency coronary artery bypass grafting. Main adverse cardiac events （MACE） were defined as a combined end point of death, non-fatal myo-cardial infarction, target lesion revascularization and rehospitalization for cardiac ischemic events. Results Patients with a CAC score〉300 （n=145） had significantly higher PCI complexity （13.1%vs. 5.8%, P=0.017） and rate of procedure-related complications （17.2%vs. 7.4%, P=0.005） than patients with a CAC score≤300 （n=189）. After a median follow-up of 22.5 months （4-72 months）, patients with a CAC score≤300 differ greatly than those patients with CAC score＆gt;300 in cumulative non-events survival rates （88.9 vs. 79.0%, Log rank 4.577, P=0.032）. After adjusted for other factors, the risk of MACE was significantly higher [hazard ratio （HR）：4.3, 95%confidence inter-val （95%CI）：2.4-8.2, P=0.038] in patients with a CAC score〉300 compared to patients with a lower CAC score. Conclusions The CAC score is an independent predictor for MACE in SAP patients who underwent PCI and indicates complexity of PCI and proce-dure-related complications.