摘要
ObjectivesTo 地址经绝期是否由比较安全和长期的结果为 atrial 纤维性颤动(AF ) 影响导管脱离(CA ) 的结果一在经历了药倔强的 AF 的一个单个 CA 过程的 743 个女病人全部的绝经前、绝经后的 women.MethodsA 单个过程回顾地被分析。在为在绝经前的女人之间的 AF 的 CA 的临床的表示和结果的差别(PreM 组， 94 个病人， 12.7%) 并且绝经后的女人(PostM 组， 649 个病人， 87.3%) 在 PreM 组的 assessed.ResultsThe 病人更年轻(P <；0.001 ) 并且不太可能有高血压(P <；0.001 ) 并且糖尿病(P = 0.005 ) 比那些在 PostM 组。二个组关于伴随物的比例是类似的僧帽形的阀门流回冠的动脉疾病，左中庭尺寸，和左室的喷射部分。与 AF 脱离有关的复杂并发症的全面的率在两个组是类似的(P = 0.385 ) 。在 43 以后(16-108 ) 后续的月，脱离的成功率在 PreM 组是 54.3% ， 54.2% 在 PostM 组织(P = 0.842 ) 。从 atrial tachyarrhythmia 复发的全面自由在两个组是类似的。经绝期没被发现是为 AF 的单个过程的 CA 的长期的结果是的 atrial tachyarrhythmia.ConclusionsThe 的复发的一个独立预兆的因素在绝经前、绝经后的女人类似。结果显示 AF 的 CA 看起来在绝经前的女人同样象在绝经后的女人安全、有效。
Objectives To address whether menopause affects outcome of catheter ablation （CA） for atrial fibrillation （AF） by comparing the safety and long-term outcome of a single-procedure in pre-and post-menopausal women. Methods A total of 743 female patients who underwent a single CA procedure of drug-refractory AF were retrospectively analyzed. The differences in clinical presentation and outcomes of CA for AF between the pre-menopausal women （PreM group, 94 patients, 12.7%） and the post-menopausal women （PostM group, 649 patients, 87.3%） were assessed. Results The patients in the PreM group were younger （P＆lt;0.001） and less likely to have hypertension （P＆lt;0.001） and diabetes （P=0.005） than those in the PostM group. The two groups were similar with regards to the proportion of concomitant mitral valve regurgitation coronary artery disease, left atrium dimensions, and left ventricular ejection fraction. The overall rate of complica-tions related to AF ablation was similar in both groups （P=0.385）. After 43 （16-108） months of follow-up, the success rate of ablation was 54.3%in the PreM group and 54.2%in the PostM group （P=0.842）. The overall freedom from atrial tachyarrhythmia recurrence was simi-lar in both groups. Menopause was not found to be an independent predictive factor of the recurrence of atrial tachyarrhythmia. Conclusions The long-term outcomes of single-procedure CA for AF are similar in pre-and post-menopausal women. Results indicated that CA of AF appears to be as safe and effective in pre-menopausal women as in post-menopausal women.
