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辅助性T细胞17与呼吸道慢性炎性疾病 被引量：1

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摘要 辅助性T细胞17 （T helper cell 17,Th17）是CD4＋T细胞亚群,分泌白介素-17、白介素-6等多种细胞因子,其分化受白介素-6和转化生长因子-β等多种细胞因子的调节.Th17细胞通过分泌白介素-17等细胞因子促进气道内中性粒细胞募集和激活,与气道慢性炎性疾病的发生发展密切相关.Th17在哮喘、慢性阻塞性肺疾病和变应性鼻炎的炎症反应中发挥重要调控作用.本文就Th17细胞的分化及其在呼吸道慢性炎症中的研究进展做一综述.
作者 谢存存 刘翔 田鹏 邹华 马赟
机构地区 中山大学孙逸仙纪念医院耳鼻咽喉头颈外科
出处 《国际耳鼻咽喉头颈外科杂志》 2014年第2期76-79,共4页 International Journal of Otolaryngology-Head and Neck Surgery
关键词 辅助性T细胞17 (T HELPER cell 17 Th17) 白细胞介素-17 (Interleukin-17) 呼吸道疾病(Respiratory TRACT Diseases)
分类号 R56 [医药卫生—呼吸系统]
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参考文献25

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二级参考文献23

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共引文献37

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国际耳鼻咽喉头颈外科杂志
2014年 第2期

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