左颞窝神经纤维瘤1例

A solitary neurofibroma arising from the temporal fossa

1病例报告患者,女,50岁,因发现左侧颞部肿物1个月余于2013年3月13日入院。肿物缓慢增长,局部偶有针刺样疼痛,无发热、头痛、眼球活动障碍及视力异常。既往有鼻咽癌病史2年,已行放疗。入院体检：神志清楚,心肺检查未见异常;颈部软,无抵抗,未触及肿大淋巴结;双侧眼球活动正常、对光反射灵敏;鼻咽部黏膜稍粗糙,未见新生物;左侧颞窝处可触及一直径约4cm的类圆形肿物,肤色、皮温如常,质韧,边界清楚,活动度差。

Neurofibromas are benign nerve sheath tumors that arise from the nonmyelinating Schwann cells.Generally,neurofibromas can be categorized into dermal and plexiform subtypes.The former subtype is usually associated with a lone peripheral nerve in the integumentary system,while plexiform tumors are associated with many nerve bundles and can originate internally.Rarely,the plexiform tumors can undergo malignant transformation.Neurofibromas are usually found in individuals with neurofibromatosis,which is an autosomal dominant disease.On occasion,an isolated neurofibroma can transpire without being associated with neurofibromatosis.Mostly,these solitary tumors tend to occur in the gastrointestinal system,and neurofibromas of the head and neck are not uncommon,but very rarely they have been reported to occur in the temporal fossa.In this report,we describe a case of a solitary neurofibroma arising from the temporal fossa.