中国南海海绵化学成份研究Ⅱ—B·C

STUDIES ON THE CHINESE SPONGE Ⅱ-B.C

从中国南海西沙群岛永胜岛附近海域采集到的一种海绵(种属未定)分离到两种新的三羟基长链酰胺类化合物S—Ⅱ(C_(49)H_(99)NO_4,M=765,m.p.138-140℃)和S—Ⅲ(C_(45)H_(93)NO_4,M=723,m.p.92—93℃),通过对它们的IR,MS,~1HNMR,^(13)CNMR及^(13)CNMR DEPT等波谱数据分析,S—Ⅱ和S—Ⅲ的结构分别确定为N-(1-乙基-3,22-二羟基)二十二烷基-2-甲基-4-羟基二十四脂肪酸酰胺和N-(1-羟甲基-2-乙基-4-甲基-3,18-二羟基)十九烷基—二十三脂肪酸酰胺。

Two new long-chain trihydroxyamides S-Ⅱ (C_(49)H_(99)NO_4,m. p. 138 - 140℃) and S - Ⅲ(C_(46)H_(93)NO_4, m. p. 92-93℃) havebeen isolated from-an unidentified sponge collected from the SouthChina Sea. On the basis of the spectral data of IR, MS, ~1HNMR,^(13)CNMR and ^(13)CNMR DEPT of them, S - Ⅱ is identified as N - (1 -ethyl - 3, 22 - dihydroxy ) docosyl - 2 - methyl - 4 - hydroxytetra cos-anamide. S - Ⅲ is N - (1 - hydroxymethyl - 2 - ethyl - 4 - methyl - 3, 18- dihydroxy) nonadecyltricosanamide.