摘要
用透射电镜及能谱仪对21例间皮瘤患者肺组织样品进行了配对研究。结果表明,闪石类石棉纤维,主要为青石棉和铁石棉纤维的含量病例组与对照组间有高度显著性差异(P<0.001)。温石棉及其他纤维分布极为相似,两组间无显著性差异(P>0.05)。相对危险度与闪石类≥5μm的长纤维、直径<0.3μm的细纤维含量有关;与闪石类<5μm的短纤维、直径≥0.3μm的粗纤维、温石棉长短纤维和其他纤维无关。本文结果为间皮瘤病因学提供了科学依据。
Lung tissue samples from 21 autopsies of mesothelioma and from matched control were examined by transmission electronmicroscopy and energy spectroscopy.The results showed that the contents of amphibole fibers of mesothelioma group weresignificantly higher than that of the control (P<0. 001).The distributions of chrysotile and all other fibers in the two groupswere similar (P>0. 05).Relative risk was related to the content of long (length≥5μm) or thin'(diameter<0. 3μm)amphibole fibers but not related to the content of shorter (Length<5μm) and thicker (diameter≥0. 3μm)amphibole fibers,and all chrysotile and other fibers.The results provided scientific basis for the etiology of mesothelioma.
出处
《中华劳动卫生职业病杂志》
CAS
CSCD
1993年第1期5-8,共4页
Chinese Journal of Industrial Hygiene and Occupational Diseases
关键词
石棉
间皮瘤
肺组织
透射电镜
Asbestos fiber
Mesothelioma
Lung tissue
Transmission electron microscopy
Energy spectrometer
