孕母及其新生儿血清维生素A含量分析

Determination of serum vitamin A level in primiparae and their neonates

对75例健康初孕妇女及其足月健康新生儿进行血清维生素A测定,并与血清蛋白质、血红蛋白、血清铁、铁蛋白、锌等进行综合分析。母亲血清VA为3.06±1.03μmol/L,高于新生儿2.74±1.0μmol/L。夏季母、子血清VA均高于秋季,但无显著性差异。孕母临界性VA缺乏占27％、新生儿占45.3％。其血清VA与血红蛋白、血清铁、血清锌呈显著正相关,与血清铁蛋白无相关性。同时VA与新生儿出生体重、胎盘重量也呈显著相关性。提示VA对铁代谢及胎儿生长发育有重要作用。因此,重视VA对母子健康的研究,对临界VA缺乏者进行干预处理,对优生优育有重要意义。

Serum vitamin A level was determined in 75 healthy primiparae and their neonates and the correlation of serum vitamin A level with the levels of hemoglobin,ferrum rotein,feritin and zinc was analyzed.The serum vitamin A level was 3.06±1.03/imol/L in the mothers and 2.74±1.0μmol/L in the neonates,and it was higher when determined in summer than when determined in autumn but the difference was of no statistical significance.The rate of subclinical vitamin A deficiency was 27 % and 45.3% in the mothers and the neonates respectively.Serum vitamin lev- el was positively correlated with the levels of hemoglobin,ferrum and zinc(P<0.05)but had no correlation with feritin level.Serum vitamin A level was positively correlated with the birth weight of the neonates and the weight of the placenta.These findings suggest that vitamin A plays an important role in ferrum metabolism and the growth and development of the fetus.It is suggested that clinicians should pay attention to the study of vitamin A since it is important for the health of both mothers and babies.for the timely therapeutic intervention of subclinical vitamin A deficiency,and for the improvement of birth quality and child upbringing.