摘要
旨在探讨解毒益气化瘀方剂四妙解毒汤抗闭塞性动脉硬化症及抗巨细胞病毒的作用机制。结果表明四妙解毒汤可通过诱导干扰素、肿瘤坏死因子、白介素 - 2的产生、增强 L AK细胞活性等活化宿主免疫功能的间接途径而发挥抗病毒作用 ,对血管内皮具有保护作用。表明四妙解毒汤的作用机制是通过对病毒感染的有效控制来防止血管内皮损伤 ,从而打断了闭塞性动脉硬化症病理过程中的起始环节。
The purpose of the experimental study is to explore the mechanism of Simiao Jiedu decoction inhibiting human cytomegalovirus(HCMV) and arteriosclerosis obliterans(ASO).The results showed that Simiao Jiedu decoction can regular the express of immunocytokines,such as interferon(IFN),interleukin 2(IL 2),tumour necrosis factor(TNF) and promote the formation of lymphokine activated killer cell(LAK cell),namely active immune function to anti virus infection In addition,it can check the injury of HCMV infection.It suggested that the basic curative mechanism of Simiao Jiedu decoction for ASO is effectively inhibiting of HCMV infection and protecting vascular endothelium. [
出处
《山东中医药大学学报》
2001年第2期125-128,共4页
Journal of Shandong University of Traditional Chinese Medicine
基金
山东省科委资助项目! (5 2 2 .0 5 7)
