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冠心病与血清胆红素水平的关系 被引量:2

Relationship between serum bilirubin and coronary heart disease
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摘要 目的观察冠心病患者血清胆红素水平的变化 ,探讨血清胆红素与冠心病的关系。方法采用Beckman公司的试剂 ,在BeckmanC× 7Delta全自动生化分析仪上检测 6 9例冠心病患者和 33例正常对照者血清胆红素水平。结果冠心病组血清胆红素 (总胆红素和间接胆红素 )明显低于正常对照组 (P <0 0 1)。结论低胆红素水平是冠心病的一种新的危险因素 ,血清胆红素尤其是间接胆红素水平可以作为冠心病发病的生化指标之一。 Objective To investigate the variation of serum bilirubin levels in coronary heart disease and to evaluate its relationship.Methods The serum bilirubin levels in 69 cases with coronary heart disease and 33 normal control subjects were examined.Results The serum bilirubin (include total bilirubin and indirect bilirubin) in coronary heart disease was lower than that in normal control subjects ( P <0.01).Conclusion Lower serum bilirubin is a new independent risk factor for coronary heart disease. The serum bilirubin levels, especially indirect bilirubin could be a chemical index in risk of coronary heart disease.
出处 《贵州医药》 CAS 2001年第4期318-319,共2页 Guizhou Medical Journal
关键词 冠心病 胆红素 诊断 危险因素 Coronary heart disease Bilirubin
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参考文献3

  • 1Wu TW, et al. Albumin-boundbilirubin protects human ventricular myocytes against oxyradical damage. Biochem CellBiol, 1991,69(10~11):683~688.
  • 2Schwertner HA, et al. Association of low serum concentration of bilirubin withincreased risk of coronary artery disease. Clin chem, 1994,40( 1 ):18~23.
  • 3Herttuala S, et al. Evidence for the presence of oxidatively modified low deneitylipoprotein in atheroslerotic lesions of rabbit and man. J Clin Invest, 1989,84:1086.

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