浙南猪冠尾线虫病及人患蚴移行症的发现

A study of epidemiology & pathogenesis of swine kidney worm disease and discovery of larva migrans in human beings in South Zhejiang

目的 :了解浙南猪冠尾线虫病流行情况和危害及其蚴对人的致病性。方法 :检测猪尿中肾虫卵及肾虫分布处的病态 ,从猪舍分离感染性蚴 ,并经口、肤感染豚鼠 ,观察杀虫药疗效。同时以免疫学检测易感人群与皮炎患者。结果 :母猪冠尾线虫感染率为 5 0 .1% ,肉猪为 14.1% ,成虫寄生于输尿管周围占 6 6 .7% ,猪的多处脏器有病变。猪舍内冠尾线虫蚴较多 ,清理猪舍者易遭蚴侵袭致皮炎 ,从匐行疹处获蚴。结论 :浙南猪冠尾线虫病流行广 ,危害性大 ;

Objective:To study epidemiology of swine kidney disease(Sephanuriasis) in South Zhejiang and its harmful and disease producing effect of larvae of Swine Kidney worms on human beings so as to provide basis for the prevention and treatment of the disease.Methods:Examining the eggs swine kidney worms in the urine and worms distribution and pathological conditions; Seperating larvae from the Pigery and infecting Guinea pigs with infective Larvae. Via mouth or skin; Obseving curative effect of the worm killing drugs; examining Susceptible Persons and patients with dermatitis.Results:Infective rate of kidney worms in femal Pigs is 50.1%; and 14.12% in flesh Pigs. Adult worms mainly harbour around the ureter(66.67%). The disease involves many viscera and the condition is Severe. There are a lot of larvae of kidney worms(Sephanurus dentatus=S.d.) in the Pigery. Those cleaning the Pigery bare footed are likely to be infected, resalting in dermatitis or rashes. Two larvae of .S.d. were doscovered from the migrant eruption node of the Petient.Conclusion:The Sephanuriasis was distributed. widely in the South Zhejiang and severely harmed to pigs. Larvae migrans of .S.d. in human was first discovered. Synthetic prophylax and treatment of Sephanuriasis were employed and desired effects were achiveved.