摘要
目的 :观察自制的纯中药普渡罗胶囊对强直性脊柱炎的疗效。方法 :采用治疗前后自身对照法 ,对 72例强直性脊柱炎患者进行临床观察。疗程 8周 ,普渡罗胶囊用量为 2~ 4粒 / d(每粒含生物总碱 2 80 mg) ,分 1~ 2次口服。 结果 :12项临床观察指标中有 9项 (晨僵、骶髂关节压痛度、扩胸度、外周关节压痛数和肿胀数、外周关节压痛积分和肿胀积分、15 m步行时间、患者与医生评估 )治疗后明显改善 (P<0 .0 1或 P<0 .0 5 ) ;实验室指标中的血小板、血细胞沉降率、γ-球蛋白 ,治疗前后比较改善显著 (P<0 .0 5或 P<0 .0 1)。在 8周疗程中除有轻度口干外 ,无其他不良反应。结论 :普渡罗胶囊治疗强直性脊柱炎不仅有镇痛消炎作用 ,而且能有效地控制病情进展。
Objective: To observe the therapeutic effects of PutRh capsule in treatment of ankylosing spondylitis(AS). Methods: Seventy two consecutive cases of AS were studied clinically, and the results before and after treatment were compared. The treatment lasted for 8 weeks. The patients were given PutRh 2 4 cpasules, 1 2 times per day. Results: Nine clinical parameters out of 12 were impoved obviously after treatment ( P <0.01, P <0.05), including morning stiff, number of peripheral joints pain, number of swelling, the deepness of tenderness of rumpbone, and so on, the comaprison of laboratry parameters was significant before and after treatment ( P <0.05, P <0.01). There were no other adverse effect except stight xerocheilia during the 8 week treatment. Conclusion:PutRh not only has analgesia and anti inflammation effects on ankylosing spondytitis, but also slows the progress of the disease. [
出处
《第二军医大学学报》
CAS
CSCD
北大核心
2001年第3期287-289,共3页
Academic Journal of Second Military Medical University
关键词
普渡罗胶囊
强直性脊柱炎
中医药治疗
AS
PutRh capsule
ankylosing spondylitis
Chinese traditional medicine therapy