胃癌序贯筛查实施现场胃癌患者术后生存分析──11年随访

Survival Analysis for Patients with Gastric Cancer Operated after Sequencial Screening of Gastric Cancer: 11 Years Follow-up

目的：探讨胃癌序贯筛查法实施后手术治疗对胃癌患者生存率的影响。方法：参加胃癌序贯筛查的人群及作为对照的非筛查人群中发现胃癌并进行手术治疗的６７例患者为研究对象，其中筛查组２７例，非筛查组４０例，自１９８７年随访至１９９７年，详细记录其生存时间等资料并进行生存分析。结果：胃癌筛查组患者术后５年及１０年生存率均明显高于非筛查组患者，存在显著统计学差异（５年生存率：７３．０％比３４．５％，Ｐ＜０．０５；１０年生存率：６９．０％比０，Ｐ＜０．０５）。筛查组早期胃癌患者的比例亦明显高于非筛查组（６３％比５％，Ｐ＜０．０５）。结论：实施胃癌序贯筛查可以探查出更多的早期胃癌，手术治疗可以明显延长患者的生存时间。

Background/Aims: To study the survival analysis for patients with gastric cancer who had been operated by sequencial screening of gastric cancer. Methods: Survival analysis of 67 gastric cancer patients who had been operated were studied in the screening group (n=27) and unscreening group (n=40) from 1987 to 1997. Results: There was significant difference in 5-year and 10-year survival rates between screening group and unscreening group (5-year survival rate: 73.0% vs 34.5%, P< 0.05; 10-year survival rate: 69.0% vs 0, P<0.05). More early gastric cancers were found in screening group than in unscreening group (63% vs 5%, P<0.05). Conclusions: Sequencial screening of gastric cancers may detect more early gastric cancers and prolong the survival period of patients with gastric cancer after surgery.