喉返神经切断后甲状舌骨肌变化的研究

Observation of thyrohyoid muscle change after cutting the recurrent laryngeal nerve in dog

目的 :研究喉返神经 (recurrent laryngeal nerver,RL N)切断后 ,甲状舌骨肌 (thyrohyoid muscle,THM)的变化。方法 :通过建立 RL N麻痹动物模型 ,应用组织化学染色及显微图像分析 ,动态地观察 THM三型肌纤维直径和面积的变化。结果 :术后双侧 THM三型肌纤维直径和面积出现进行性下降。实验组在 8～ 10周 ,对照组在 6～ 8周达最小 ,至2 0周恢复。结论 :THM的变化可能与手术创伤及营养有关 ,而与切断 RL N无关。

Objective.To observation the change of thyrohyoid muscle(THM)after recurrent laryngeal nerve(RLN)has been cutting off.The animal experimental results were reported.Method.The animal experimental model of RLN paralytic was completed in 9 dogs.The specimens of THM were treated by histochemiscal staining after 2,4,6,8,10,20 day operation respectively and the diameter and areas of three types muscle fibers were determined by microscope.Results.The diameters and areas about 3 types muscle fibers of THM descended after operation,the value of them reached the minimum simutaneously,then recovered step by step.Conclusion.The changes of THM was related to operative trauma and nutrition disorder probably,while it was not related to RLN cutting.