Ⅰ型及Ⅱ型银屑病发病危险因素分析

Analysis of the Risk Factors in TypeⅠ and type Ⅱ Psoriasis

目的研究Ⅰ、Ⅱ型银屑病发病危险因素。方法采用病例－对照研究方法，调查了Ⅰ、Ⅱ型银屑病患者分别为５８１例、１１７例及同一地区的年龄相匹配正常对照组分别为５３４例与１１２例，对Ⅰ、Ⅱ型银屑病的危险因素进行研究。结果①吸烟、嗜酒、食鱼虾、药物、受潮、感染、精神紧张、接种疫苗为Ⅰ型银屑病发病的危险因素。②嗜酒、食鱼虾、受潮、感染、精神紧张为Ⅱ型银屑病发病的危险因素。③吸烟为男性发生Ⅰ型银屑病的危险因素；嗜酒为男性发生Ⅰ型及Ⅱ型银屑病的危险因素；精神紧张在Ⅰ型及Ⅱ型银屑病男女患者中无显著性差异。结论环境因素在Ⅰ、Ⅱ型银屑病发病中起一定作用。

Objective To study the risk factors of type Ⅰ and type Ⅱ psoriasis. Methods We used the case-control study and standardized questionnaires. The 581 type Ⅰ psoriasis, 117 type Ⅱ psoriasis,534 and 112 controls that collected in the clinic were investigated. Results ①The risk factors of type Ⅰ psoriasis were smoking, drinking, eating fish and shrimp, drugs, mois- ture, infection, vaccination and sires. ②The risk factors of type Ⅱ psoriasis were drinking, eating fish and shrimp, moisture, in- fection and stress. ③Smoking was the risk factor of type Ⅰ psoriasis in man. Drinking was the risk factor of type Ⅰ and type Ⅱ psoriasis in man. Stress had not difference in man and woman with type Ⅰ and type Ⅱ psoriasis. Conclusion These studies sug- gested that environmental factors may play an important role in type Ⅰ and type Ⅱ psoriasis.