摘要
目的 评价国产离子型对比剂的临床安全性 ,并与进口非离子型对比剂进行比较。方法 10 96例CT增强扫描中 ,86 4例使用 76 %复方泛影葡胺 ,2 32例使用优维显 ,对比其不良反应和影像质量。前者又随机分组 ,2 73例CT增强前静脉注射地塞米松 ,5 91例未用地塞米松 ,观察预防用药的作用。结果 76 %复方泛影葡胺总的和轻中度不良反应的发生率高于优维显 ,重度和死亡不良反应的发生率与优维显近似 ,影像质量好于优维显。预防用药可减轻各种程度的不良反应。结论 对无高危因素的患者 ,预防用药后 。
Purpose To evaluate the clinical safety of ionic contrast media made in china and compare with nonionic contrast media being imported. Methods Among contrast enhanced CT 1096 cases, 76% meglumine diatrizoate were administed in 864 cases and ultravist in 232 cases , comparative studies on adverse drug reactions(ADRs) and image quality were performed. Results In 76% meglumine diatrizoate group , the prevalence of overall and mild middle ADRs was higher than in the ultravist group , the prevalence of severe and potentially life threatening ADRs was approximate in the ultravist group , the image quality was well than in the ultravist group.Preventive inoculation alleviated ADRs at all levels. Conclusion Ionic contrast media made in china was safe and effective in patients without hyperthyroidism after preventive inoculation. [
出处
《中国医学影像技术》
CSCD
2001年第3期283-285,共3页
Chinese Journal of Medical Imaging Technology
