二尖瓣置换术后芬太尼经静脉患者自控镇痛的可行性

The Efficacy of Patient Controlled-analgesia with Fentanyl in Mitral Valve Replacement of the Patients

目的 探讨二尖瓣置换术 ( MVR)术后早期芬太尼经静脉患者自控镇痛的有效性和安全性。方法 3 0名 MVR术后患者随机分为两组 :CAT组为常规止痛组 ;PCA组为芬太尼经静脉患者自控止痛组。术后 48h内观察止痛效果和呼吸、循环功能指标。结果 休息时及活动、咳嗽时的 VAPS评分 PCA组在各时间段均明显低于 CAT组 ( P<0 .0 1和 P<0 .0 5 )。两组血流动力学和呼吸功能指标均在正常范围内波动。结论 芬太尼经静脉患者自控止痛可以安全、有效地缓解术后疼痛 ,但在应用中仍需严密监测。

Thirty patients who were planned to undergo mitral valve replacement(MVR) were enrolled in this study. They were divided into 2 groups:Group CAT (conventional analgesia treatment) and Group PCA (patient controlled analgesia).The results of analgesia , parameters of hemodynamics and blood gas results were observed 48 h after the operation.Rest and exercise VAPS scores of the 2 groups showed significant difference. Both the hemodynamics and respiratory parameters of the 2 groups were in the normal range(P<0.01 and P<0.05).Conclusion showed that fentanyl PCA was an effective and safe analgesia for MVR patients under intensive care.