美泰宁对睡眠作用的影响研究

Study on the Effect of Melatonin on Mice's Sleep

目的 观察美泰宁对小鼠睡眠的影响。方法 按《中药药理研究方法学》中改善睡眠检验方法进行测定。结果 中、高剂量组能明显延长戊巴比妥钠诱导的睡眠时间及增加戊巴比妥钠诱导的睡眠发生率(P<0.01)。结论 美泰宁具有改善小鼠睡眠的作用。

Objective To observe the efiiect of raelatonin on sleep of mice.Methods The improvement sleep of mice was as-sayed according to test methods of improvement sleep function in 《methodological Study of Chinese Herbs phamiacology》 . Results It showed that there was significant difference in sleep time and incidence of pentobarbital sodium induced among the test and control groups after 30 days administeration (P < 0.01) .Cooclusion Melatonin can improve sleep of mice.