镍钛记忆合金网状支架在BPH患者的应用及远期疗效观察

Use of the Memotherm^(TM) stent in benign prostatic hyperplasia:long-term results

目的 :观察镍钛记忆合金网状支架治疗良性前列腺增生症 (BPH)的疗效及安全性。方法 :38例患者使用镍钛记忆合金网状支架治疗 ,除了 5例患者失访 ,其余 33例患者都得到观察或随访。结果 :除了 2例患者因膀胱逼尿肌功能丧失而治疗失败 ,其他患者都可自行排尿 ,2例患者因支架移位而取出 ,3例患者在 2年后恢复留置导尿 ,15例患者在 31～ 48个月后得到随访 ,其 IPSS评分为 2 1.2± 4.3分。结论 :镍钛记忆合金网状支架对治疗BPH是一种有效的措施 ,特别适用于不能耐受手术或预期寿命不长的尿潴留患者。

Purpose:To determine the long term safety and efficacy of the Memotherm TM endoprosthesis as a therapeutic alternative in the management of men with BPH.Method:Memotherm TM urethral stent was applied to thirty eight men (mean age 77 years. Range 62 87 ) with symptoms and urodynamics suggestive of BPH.Results:Follow up was lost in five patients. All but two patients with follow up were eventually able to have spontaneous urination. Stents were removed from two patients because of dislocation. Prostatectomy was required in three patients at 15, 30 and 32 months respectively. Three patients resorted to indwelling catheterization after two years due to recurrence of symptoms. Information on 15 patients between 31 and 48 months follow up was obtained. IPSS score was 21.2 ± 4.3 .Conclusion:The long term results from our trial unveiled that the Titanium alloy memorial stents was an effective therapeutic alternative for patients having urinary retention with short life expectancy or operative contraindication.