COPD患者外周血几项免疫指标的变化

Study the Variety of Serum Interleukin-2 Receptor, Interleukin-8, Immunoglobulin, T-lymphyocyte Subgroup in Patients with COPD

为了探讨COPD患者外周血可溶性白细胞介素 2受体 (sIL - 2R)、白细胞介素 - 8(IL - 8)、免疫球蛋白、T淋巴细胞亚群水平变化 ,用ELISA法检测COPD患者 30例 ,对照组 30例 ,血清sIL - 2R ,IL - 8;免疫散射速率法测IgG ,IgA ;单克隆抗体免疫组化萤光染色法测CD+ 3 ,CD+ 4,CD+ 8,并进行分析 .结果COPD患者sIL - 2R ,IL - 8,CD+ 8增高 ;IgG ,IgA ,CD+ 3 ,CD+ 4,CD+ 4/CD+ 8比值均降低 ,具有较显著性差异 .提示COPD患者免疫功能低下 .

To study the variety of sIL-2R, Il-8, immunoglo bulin, T-lymphycyte subgroup in patients with COPD. 30 cases with COPD and the control group of 30 cases were d etected sIL-2R, IL-8 with ELISA; IgG, IgA with rate nephelometry; CD + 3,CD + 1, Cd + 3,with immunoflu orescence. Results: Patients with CO-PD sIL-2R, Il-8, CD 8 increase and IgG, IgA, CD + 3, CD + 4,CD + 4/CD + 8 decrease. The difference is very significant. Conclusion: The immuni faction of patients with COPD reduce.