1994-1999年上海市抗生素用量分析

1994-1999 antibiotics consumption analysis in Shanghai

目的 :了解上海市抗生素用量的变化趋势。方法 :选取 1994- 1999年上海市医院用药分析系统中的抗生素类药品数据资料 ,将每种抗生素的用量折算成 DDDS/人×年 ,以年为时间单位 ,以 1994年为基准年 ,分析抗生素用量的变化。结果 :上海市抗生素总量用呈逐年增长趋势。从用量构成比来看 ,以头孢菌素类为最大 ,其中以头孢拉定用量最多。从用量增长率来看 ,以青霉素复合制剂为最高 ,青霉素类次之 ,青霉素复合制剂中的羟氨苄青霉素克拉维酸盐增长率最高。结论 :上海市抗生素总用量呈上升趋势 ,应用最多的是中等价格的头孢菌素类药 ,增长最快的是高价青霉素复合制剂 。

AIM: To estimate the trend of antibiotics consumption in Shanghai. METHODS: Antibiotics data were selected from Hospital Purchasing of Drug Information System (HPDIS) from 1994 to 1999. Each antibiotic consumption was converted into DDDs/inhabitant×year, year was used as time unit, and 1994 was regarded as beseline year. RESULTS: Total antibiotics consumption increased annually. According to the proportion, cephalosporins was in the first rank, and in this category, cefradine consumption was the most. According to the annual growth rate, penicillin compound preparation was in the first rank, penicillins was in the second rank. The growth rate of amoxicillin/clavulanate potassium was the highest one in the penicillin compound preparation. CONCLUSION: Antibiotics consumption was increasing rapidly in Shanghai, particularly penicillin compound preparation with high price. Cephalosporins with medium price was used more frequently than others. That was the main reason for the escalation of antibiotics expenditure.