摘要
应用银胶染色技术对46例皮肤肿瘤石蜡切片进行Ag-NOR定量观察。结果表明,皮肤乳头状瘤Ag-NOR计数平均为1.3个/核;基底细胞癌Ag-NOR计数平均为5.6个/核;高分化鳞癌Ag-NOR计数平均为2.4个/核;低分化鳞癌Ag-NOR计数平均为5.3个/核。
A silver colloid staining techniqne to identify nucleolar organize region associated protein (Ag-NOR) has been applied to 46 cutaneous tumours. These comprised 9 papillomas, 14 basal cell carcinomas and 23 squamous cell carcinomas. It was observed that average of papillomas was 1.3 Ag-NORs per nucleus, basal cell carcinomas 5.6 Ag-NORs per nucleus, and number of AgNORs for squamous cell carcinoma was varied between 2.4 and 5.3 depending on their differentiation. The differences were statistically significant (P<0.01) . It is suggested that technique may be of use for diagnosis of cutaneous neoplasm.
出处
《哈尔滨医科大学学报》
CAS
1991年第6期416-418,485,共3页
Journal of Harbin Medical University
关键词
皮肤肿瘤
组织化学技术
RNA
DNA
Histochemistry technique
Cutaneous tumor
Nucleolar organizer region
DNA
RNA
