七星草乌化学成分的研究

Studies on the Chemical Constituents of the Aconitum Contortum Finet et Gagnep

从毛茛科植物七星草乌的根中分离得到四个新化合物和一个已知化合物,根据它们的物理化学常数和IR,UV,~1H NMR,^(13)C NMR和MS分析,分别确定为七星草乌碱(conaconitine)(1),N,N-双(甲氨甲酰基)-甲胺[N,N-bis(methylcarbamyl)-methyl amine](2),三(甲氨甲酰基)-胺[tris(methylcarbamyl)amime](3),1-(1-溴乙基)-4 -(1,2-二溴乙基)-苯[1-(1-bromoethyl)-4-(1,2-dibromoethyl)-benzene](4)和已知化合物对-双(1,2-二溴乙基)-苯[p-bis(1,2-dibro-moethyl)-benzene](5)。

Four new compounds, conaconitine, N, N-bis (methylcarbamyl)-methyl amine, tris(methylcarbamyl) amine, 1-(1-bromoethyl)-4-(1, 2-dibromoethyl) benzene and the known compound p-bis (1, 2-dibromoethyl) benzene have been isolated from the root of Aconitum Finet et Gagnep. Their structures were established on the basis of spectral analysis (UV, IR, MS, ~1H and ^(13)C NMR).