黄芪注射液对哮喘患者气道反应性的影响

Influence of Radix Astragali Injectio on Airway Reactivity of Asthmatics

目的：探讨黄芪注射液对降低气道反应性的治疗作用。方法：选取２５例志愿用黄芪注射液的哮喘患者，治疗前测定用力肺活量（ＦＶＣ）、１秒钟用力呼气客积（ＦＥＶ１；）及高峰呼气流速（ＰＥＦ），并用乙酰甲胆碱（Ｍｃｈ）累积量０．０３３μｍｏｌ和１．９８μｍｏｌ作激发试验，治疗后再次测定这３项指标。 结果：所有患者经黄芪注射液治疗后，一般情况明显改善，ＦＶＣ、ＦＥＶ及ＰＥＦ明显增加（Ｐ＜０．０５、Ｐ＜０．０１、Ｐ＜０．０１）。结论：黄芪注射液能够改善哮喘患者的一般情况，降低哮喘患者的气道反应性。

Objective: To explore the effect of Radix Astragali Injectio (RAJ) on lowering the airway reactivity. Methods: 25 cases of asthma recieving RAI were subjected to the study. The forced vital capacity (FVC), one - second forced expiratory volume (FEY1) and peak expiratory flow rate were measured before and after treatment respectively, with 0. 033 mol and 1. 98 mol accumulated volume of methacholine for excitation tests. Results: The general condition of patients was markedly improved, FVC, FEY1 and peak expiratory flow were significantly increased (P <0. 05, P <0. 01, P < 0. 01 respectively) . Conclusion: RAI can improve the general condition and lower the airway reactivity of asthmatics.